Endocrine Abstracts

Intentional insulin overdose in diabetic patients is a rare critical situation. The severity is due to numerous neurological complications, electrolyte disturbances, liver and lung damage or death.A 76-years old female, with significant cardiac pathology, diagnosed with type 2 diabetes and treated with Humalog Mix50® 0-0-24 U/day, is admitted to our center via ER (emergency room) after an episode of severe hypoglycemia after administratio...

Polyglandular autoimmune syndromes (PAS) are a heterogeneous group of rare diseases characterized by autoimmune activity against more than one endocrine organ, although non-endocrine organs can be affected. In PAS III, autoimmune thyroiditis occurs with another organ-specific autoimmune disease, but the syndrome cannot be classified as PAS I or II.A 29-years old man was refer to our center for diagnostic confirmation with the following complaint...

Insulinoma represents one of the most encountered neuroendocrine tumors, but only 4–14% is malignant. The diagnosis is suggested by high serum insulin levels during spontaneous or induced episodes of hypoglycemia and often invasion of lymph nodes and liver metastasis. A 55–year–old female was referred to our center after an episode of hypoglycemia during strumectomy for multinodular goiter. Further questioning revealed few years of Metformin treatment for hyp...